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Chloral hydrate

CAS No. 302-17-0

Chloral hydrate( NSC 3210 )

Catalog No. M13945 CAS No. 302-17-0

Chloral Hydrate is a synthetic monohydrate of chloral with sedative, hypnotic, and anticonvulsive properties.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Chloral hydrate
  • Note
    Research use only, not for human use.
  • Brief Description
    Chloral Hydrate is a synthetic monohydrate of chloral with sedative, hypnotic, and anticonvulsive properties.
  • Description
    Chloral Hydrate is a synthetic monohydrate of chloral with sedative, hypnotic, and anticonvulsive properties. Chloral hydrate is converted to the active compound trichloroethanol by hepatic alcohol dehydrogenase. The agent interacts with various neurotransmitter-operated ion channels, thereby enhancing gamma-aminobutyric acid (GABA)-A receptor mediated chloride currents and inhibiting amino acid receptor-activated ion currents. In addition, chloral hydrate enhances the agonistic effects of glycine receptors, inhibits AMPA-induced calcium influx in cortical neurons, and facilitates 5-HT 3 receptor-mediated currents in ganglionic neurons. Overall, this results in a depressive effect on the central nervous system.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    NSC 3210
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    GAT
  • Recptor
    GABAR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    302-17-0
  • Formula Weight
    165.4
  • Molecular Formula
    C2H3Cl3O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mM
  • SMILES
    OC(O)C(Cl)(Cl)Cl
  • Chemical Name
    2,2,2-Trichloroethane-1,1-diol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Delgado J, et al. Pediatr Radiol. 2015 Jan;45(1):108-14
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